cpsp.pharmacy.ufl.eduCenter for Pharmacometrics & Systems Pharmacology » College of Pharmacy » University of Florida

Center for Pharmacometrics & Systems Pharmacology » College of Pharmacy » University of FloridaHome - current page Meet the team Research TrainingShow submenu for Overview Awards/Recognitions 2011 2012 2013 2014 2015 2016 2017 2018 2019 2021 2022 Testimonials Ana Alarcia Lacalle, B. Pharm. Miriam Happ, B.Pharm Marian Klose, B.Pharm Karthik Lingineni, Ph.D. Estevan Zimmermann, Ph.D. Puneet Gaitonde, Ph.D. Chaejin Kim, Ph.D. Amit Somani, Ph.D. Jiexin Deng, Ph.D. Xiling Jiang, Ph.D. Songmao Zheng, Ph.D. Contact Us University of Florida Research and Academic Center, Lake Nona, FL Mission The Center’s purpose is to create a uniquely rigorous and integrative academic translational science program in quantitative clinical pharmacology with a focus on personalized medicine. Integral to this mission is the education and training of doctoral students and post-doctoral fellows in the discipline of drug development and regulatory science (DDRS). Using systems biology approaches, researchers study drug activities, targets and clinical effects to support and advance translational research, which improves the process of bringing new drugs to market for improved patient therapies, including personalized medicines. Goals and Objectives The Center’s programs, enabled through five pillars, support its mission to: Train DDRS practitioners with customized subspecialties and research areas related to drug development, regulatory, clinical practice or methods development. Conduct applied research proximal to clinical trials and/or clinical practice oriented toward problem solving through quantitative analysis, drug-disease modeling/simulation, and clinical trial design. Establish partnerships with industry in context of drug development programs supporting data analysis and decision-making as well as regulatory strategies. Serve as a neutral forum among industry, FDA and other stakeholders to encourage multi-directional communication, and policy development to facilitate advancement of DDRS. Disseminate new knowledge through credible publications and presentations and become an influential voice for DDRS to demonstrate the value of pharmacometrics and systems pharmacology. Research Interests Cancer Cardiovascular diseases Diabetes & Obesity Infectious diseases Orphan drugs Special patient populations, such as pediatric rare diseases Our Research Focuses On Improving success rates of phase II and III clinical trials by applying modeling and simulation techniques to de-risk clinical trials by allowing for more informed decision-making Development of physiologic and mechanism-based disease models, particularly in the area of diabetes, obesity, cardiovascular, and oncology in close collaboration with our partners in industry and in Orlando Improving drug safety through the use of systems pharmacology knowledge platforms delineating causal pathways to adverse events Integrating novel technology into the drug development science to facilitate the identification, qualification, and implementation of biomarkers and approvable endpoints, including metabolomics and proteomics Center for Pharmacometrics & Systems Pharmacology College of Pharmacy Utility Links College of Pharmacy Physical Address 6550 Sanger Road, Office 465 Orlando, FL 32827-7400 Phone 407-313-7050 Make a Gift Giving Opportunities Social Media Facebook Twitter Instagram YouTube LinkedIn University of Florida Health - Home University of Florida - Home Log in Website Support Sitemap Disclaimer & Permitted Use Disability Services Security Policies UF Privacy Policy Shands Privacy Policy This page uses Google Analytics (Google Privacy Policy) © 2024 University of Florida...